
What is Medterra?
Medterra is known for its premium-grade, THC-free CBD products made from organically grown hemp. They’re certified by the U.S. Hemp Authority and offer a wide selection of broad-spectrum and isolate CBD formulations.
Why Medterra?
- THC-free formulas
- Lab-tested for purity
- Affordable subscription options
- Backed by medical advisors
Pros
THC-Free Options Available: Ideal for professionals, athletes, and those who prefer zero-THC products.
U.S. Hemp Authority Certified: Guarantees strict quality standards and traceability.
Medical-Grade Formulas: Developed with input from health professionals and backed by third-party lab testing.
Broad Product Range: Includes tinctures, capsules, gummies, topicals, and pet CBD products.
Great for Beginners: Clear labeling, dosing guides, and educational content make it user-friendly.
Cons
Less Entourage Effect: Many products are THC-free, which may reduce synergistic benefits of full-spectrum CBD.
Premium Pricing: Slightly more expensive than some competitors for equivalent dosages.
Limited Flavor Options: Tinctures and gummies come in fewer flavors compared to lifestyle brands.

What is Soul CBD?
Soul CBD has carved out a niche in wellness-forward CBD, offering flavorful gummies, tinctures, and capsules designed to support sleep, stress, and focus. Their branding is vibrant, and their community-first approach resonates with younger consumers.
Why Soul CBD?
- Gluten-free, vegan-friendly
- CO2 extraction method
- Broad-spectrum hemp extract
- Excellent flavors (like Raspberry Lemonade)
Pros
Zero THC in All Products: Perfect for those avoiding THC entirely due to personal or professional reasons.
Flavor-Focused Gummies and Oils: Fun, fruity flavors make daily CBD enjoyable and accessible.
Specialized Formulas: Includes products targeting sleep, stress, and immune support.
Vegan, Gluten-Free, and Allergen-Free: Clean label makes it ideal for sensitive users.
Female-Led Wellness Brand: Strong focus on mental health, transparency, and community support.
Cons
Isolate-Only Products: Lacks the full-spectrum or broad-spectrum entourage effect.
Higher Cost Per mg: Premium branding and formulas come at a slightly higher price point.
Limited Product Variety: Smaller range compared to larger brands—mostly focused on gummies and tinctures.

What is Five CBD?
As the name suggests, Five CBD offers full-spectrum products with a 5:1 ratio of CBD to other beneficial hemp compounds like THC, CBN, and CBC. This delivers an enhanced entourage effect, giving you more therapeutic value per dose.
Why Five CBD?
- Transparent cannabinoid breakdown
- One of the highest THC limits legally allowed
- U.S.-grown hemp with third-party testing
- Subscription savings available
Pros
High Potency Full-Spectrum Formulas: Contains a powerful 5:1 ratio of CBD to minor cannabinoids and terpenes.
Includes Legal THC (up to 0.3%): Enhanced entourage effect for noticeable results.
Third-Party Lab Tested: Transparent COAs available for every product batch.
Unique Product Options: Includes full-spectrum chocolates and potent CBD+THC gummies.
Great for Experienced Users: Offers strong effects for those with higher tolerances or advanced needs.
Cons
May Be Too Potent for Beginners: Full-spectrum products with THC can be overwhelming for new users.
Not Ideal for Drug-Tested Professionals: Even trace THC can cause positive drug tests.
Limited THC-Free Options: Focus is primarily on full-spectrum formulas.

What is Plus CBD?
One of the earliest and most research-driven CBD companies, Plus CBD is known for clinical-grade products that combine natural plant compounds with rigorous scientific testing.
Why Plus CBD?
- Non-GMO, gluten-free, and vegan
- Advanced formulations with botanicals
- U.S. Hemp Roundtable member
- cGMP-certified facility
Pros
Trusted Pioneer Brand: Among the first CBD brands in the U.S. to offer hemp extracts with scientific backing.
Clinically Researched: Products supported by scientific data and internal studies.
Triple Lab Tested: Ensures safety, consistency, and potency from seed to shelf.
Diverse Product Range: Tinctures, sprays, softgels, gummies, balms, and even skincare items.
Widely Available: Sold in major retailers like CVS, Sprouts, and online.
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Cons
Outdated Packaging: Some product lines lack modern design and appeal compared to newer brands.
Flavor Profile is Mild: Not as appealing to users seeking fruity or bold flavor options.
Some Products Use Conventional Sweeteners: Not ideal for those avoiding processed ingredients.

What is Canna River?
Canna River is known for delivering bulk-sized, affordable CBD and Delta-8 products without compromising on quality. Their branding is minimal, but their offerings are potent and versatile.
Why Canna River?
- Some of the highest milligram options on the market
- Non-GMO, American-grown hemp
- Broad and full-spectrum formulas
- Free shipping on all U.S. orders
Pros
High-Potency CBD at Affordable Prices: Offers tinctures up to 12,000mg without breaking the bank.
Broad and Full Spectrum Options: Flexible for users who want THC-free or THC-included formulas.
Large Bottle Sizes: More value per dollar and longer-lasting supplies.
Clean, Simple Ingredients: No unnecessary fillers or synthetic additives.
Appealing to Budget-Conscious Users: Quality doesn’t come with a luxury price tag.
Cons
Strong Potency May Intimidate New Users: Not ideal for beginners who need lower dosages.
Limited Physical Retail Presence: Primarily available online, which can delay access.
Less Emphasis on Lifestyle Branding: No targeted formulas or wellness themes (e.g., sleep, focus).
Conclusion
When it comes to choosing the best CBD brand, it’s all about finding the right balance between quality, potency, transparency, and your individual wellness goals. With the wide range of CBD products available today — from tinctures and gummies to topicals and capsules — identifying a trusted brand is crucial to experiencing the full benefits of cannabidiol.
Whether you’re searching for THC-free peace of mind, high-dosage support, or targeted relief for sleep, stress, or inflammation, the five brands we’ve highlighted — Medterra CBD, Soul CBD, Five CBD, Plus CBD, and Canna River — represent some of the most reliable, lab-tested, and consumer-trusted names in the industry.
Medterra CBD offers clinical-grade, THC-free solutions ideal for professionals and athletes.
Soul CBD is perfect for beginners and flavor lovers seeking wellness without the high.
Five CBD delivers one of the strongest full-spectrum experiences available with a powerful entourage effect.
Plus CBD brings research-driven, pharmacy-quality products backed by years of clinical testing.
Canna River is the ideal choice for budget-conscious users who still want high potency and clean ingredients.
Each of these companies prioritizes third-party lab testing, organically grown U.S. hemp, and transparent manufacturing processes, ensuring you’re getting the highest quality product every time. They also offer a variety of strengths, flavors, and delivery methods to suit every lifestyle — whether you need daily support, occasional relief, or a better night’s sleep.
As with any supplement, it’s always best to start with a lower dose and gradually increase until you find what works best for your body. Consulting with a healthcare provider, especially if you’re taking other medications, is also a smart move.
In a rapidly growing market where quality can vary widely, sticking with these trusted, top-rated CBD brands gives you peace of mind — and a much better chance at experiencing real, noticeable results.